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Progesterone ELISA

Progesterone ELISA
Catalog Number:     Progesterone HU-LB26
Description:             Progesterone ELISA
Sample Type:           Serum
Sample Size:            25 µl
Available Sizes:       96 Wells
Range:                     0-50 ng/ml
Sensitivity:               0.3 ng/ml
Incubation:              1 hour(s) 50 minutes (s)
Protocol:                  Progesterone ELISA
Regulatory Status:  RUO
Product Distribution: Available worldwide

Progesterone ELISA is for the direct quantitative determination of Progesterone by enzyme immunoassay in human Serum.
Progesterone is the major female sex hormone. This steroid is responsible for reproductive-related activities
such as breast glandular development, the endometrial aspects of the menstrual cycle, and the establishment and maintenance of pregnancy. In addition, progesterone also directs pregnancy-support physiology including changes in carbohydrate, protein and lipid metabolism, thermoregulation, sodium reabsorption in renal tubules and the reduction of alveolar and atrial carbon dioxide partial pressures (PCO2). Progesterone is involved in cell cycle progression, acts as a neurosteroid to promote remylination of nerve axons and is used therapeutically to treat menopause-related symptoms in women. Progesterone is secreted in large amounts by the corpus luteum and by the extracellular conversion of cholesterol, cholestryl esters, adrenal steroids, prenenolone and pregnenolone sulfate. Small quantities are also secreted directly from the adrenal glands.
Since sex steroids are not stored, progesterone is quickly cleared from circulation by extracellular conversion to androgens or estrogen, or to preganediol which is conjugated to glucuronic acid in the liver and excreted in urine. Only a small portion of circulating plasma progesterone is free (2.4%) with the remaining steroid bound to serum proteins.