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Ferritin ELISA

Ferritin ELISA
Catalog Number: Ferritin HU-LB15
Description: Ferritin  ELISA
Sample Type: Serum
Sample Size: 20 µl
Available Sizes: 96 Wells
Range: 0-1000 ng/ml
Sensitivity: 1.0 ng/ml
Incubation: 1 hour(s) 15 minutes (s)
Protocol: Ferritin  ELISA
Regulatory Status: RUO
Product Distribution: Available worldwide

Ferritin ELISA - Enzyme Immunoassay for the Quantitative Determination of Human Ferritin Concentration in Human Serum.
One of the most prevalent disorders of man is the dietary deficiency of iron and the resulting anemia.
Iron-storage compounds in the body include hemoglobin, hemosiderin, myoglobulin, and the cytochromes. In most tissues, ferritin is a major iron-storage protein. Human ferritin has a molecular weight of approximately 450,000 daltons, and consists of a protein shell around an iron core; each molecule of ferritin may contain as many as 4,000 iron atoms. Under normal conditions, this may represent 25% of the total iron found in the body. In addition, ferritin can be found in several isomers.
High concentrations of ferritin are found in the cytoplasm of the reticuloendothelial system, the liver, spleen, and the bone marrow.
The measurement of ferritin in serum is useful in determining changes in body iron storage, and is non-invasive with relatively little patient discomfort. Serum ferritin levels can be measured routinely and are particularly useful in the early detection of iron-deficiency anemia in apparently healthy people.
Serum ferritin measurements are also clinically significant in the monitoring of the iron status of pregnant women, blood donors, and renal dialysis patients. High ferritin levels may indicate iron overload without apparent liver damage, as may be noted in the early stages of idiopathic hemochromatosis. Ferritin levels in serum have also been used to evaluate clinical conditions not related to iron storage, including inflammation, chronic liver disease, and malignancy.